the.com/patient zero

The first domino, forever blamed for everyone else falling.

means The first identified case in an outbreak, traced back to find how and where a disease started spreading.

from Born in epidemiology, where investigators number infected individuals during an outbreak investigation; 'patient zero' marks the index case the chain is traced from. The term got a jolt of infamy in the 1980s AIDS crisis, when a Canadian flight attendant was mislabeled in media and later research as the origin of the North American epidemic — a claim since debunked, but the phrase had already escaped into the wild, now used for the first case of anything, literal or metaphorical.

term origin
Coined during 1980s AIDS epidemiologic investigation
actual meaning
First documented case, not always the true source
famous myth
Original flight attendant case was later proven innocent
modern use
Now slang for any outbreak's unlucky origin story
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