the.com/allergy

Your immune system mistaking pollen for a home invader and calling in an airstrike.

means An overreaction by your immune system to a normally harmless substance, treating it like a dangerous threat.

from Coined in the early 1900s from Greek 'allos' (other, different) plus 'ergon' (work or action) — literally 'altered reactivity.' A doctor introduced it to name a puzzling pattern he was seeing: bodies responding abnormally to things that shouldn't provoke a response at all. The word was built deliberately as medical shorthand, not a folk tale — but it's held up remarkably well for describing an immune system that's technically doing its job, just aimed at the wrong target.

original meaning
Von Pirquet meant any changed immune response, good or bad
culprit cells
Mast cells dump histamine like a false fire alarm
peanut paradox
Early peanut exposure in infancy now prevents allergy, not causes it
evolutionary theory
Allergies may be leftover defenses against parasites and toxins
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